Acromegaly
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Acromegaly: A Comprehensive Overview
Acromegaly: A Comprehensive Overview SummaryAcromegaly is a rare endocrine disorder caused by a benign pituitary somatotroph adenoma that secretes excess growth hormone (GH), leading to elevated insulin‑like growth factor‑1 (IGF‑1) and progressive tissue hypertrophy. The prevalence is approximately 5.9 per 100 000 people, with an incidence of 0.38 per 100 000 person‑years. Diagnosis is often delayed by 5–6 years due to insidious symptom…
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Discover the World of Rare Diseases: Challenges and Breakthroughs
Discover the World of Rare Diseases: Challenges and Breakthroughs The world of rare diseases is vast, complex, and often underexplored. Although they affect a small portion of the global population, these conditions pose enormous challenges for patients and their families. Each of these diseases has unique, often invisible characteristics, making early diagnosis and appropriate treatment difficult. In this space, we…
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